Cajun Chicken Pasta Bake

Featured in: Cozy Weeknight Dinners

This dish blends tender chicken with vibrant Cajun seasonings, sautéed peppers, and onions, all coated in a creamy cheese sauce. Cooked pasta is mixed in, then baked until bubbly and golden. The combination creates a rich, comforting casserole perfect for family dinners or gatherings. Garnished with fresh parsley and an extra sprinkle of Cajun spice, it balances heat and creaminess beautifully.

Updated on Sat, 15 Nov 2025 10:11:00 GMT
Golden, bubbly baked Cajun Chicken Pasta, with creamy sauce and melted cheese for a hearty meal. Pin
Golden, bubbly baked Cajun Chicken Pasta, with creamy sauce and melted cheese for a hearty meal. | crumbkiss.com

A vibrant comforting casserole featuring tender chicken spicy Cajun seasonings creamy sauce and melty cheese all baked with pasta for a crowd-pleasing meal.

I first made this Cajun Chicken Pasta Bake on a chilly evening when I craved something cozy and filling but wanted a bit of a spicy kick. This dish quickly became a family favorite for its rich flavors and bubbly cheesy topping.

Ingredients

  • Chicken breasts: 2 large cut into bite-sized pieces
  • Red bell pepper: 1 diced
  • Yellow bell pepper: 1 diced
  • Red onion: 1 small diced
  • Garlic: 2 cloves minced
  • Penne or rigatoni pasta: 300 g (10 oz)
  • Olive oil: 2 tbsp
  • Butter: 1 tbsp
  • Heavy cream: 200 ml (¾ cup)
  • Milk: 120 ml (½ cup)
  • Shredded mozzarella cheese: 100 g (1 cup)
  • Grated Parmesan cheese: 50 g (½ cup)
  • Shredded cheddar cheese: 100 g (1 cup)
  • Cajun seasoning: 1½ tbsp plus extra for garnish
  • Smoked paprika: ½ tsp
  • Salt: ½ tsp
  • Black pepper: ¼ tsp
  • Chili flakes: ¼ tsp (optional for extra heat)
  • Fresh parsley: 2 tbsp chopped (for garnish)

Instructions

Preheat Oven:
Preheat your oven to 200°C (400°F).
Cook Pasta:
Cook the pasta in salted boiling water 2 minutes less than package instructions (it will finish cooking in the oven). Drain and set aside.
Sauté Chicken:
In a large skillet heat olive oil and butter over medium-high heat. Add chicken 1 tbsp Cajun seasoning salt and pepper. Sauté until browned and cooked through about 6–8 minutes. Remove chicken and set aside.
Cook Vegetables:
In the same skillet add onions and bell peppers. Cook for 4–5 minutes until softened. Add garlic smoked paprika and chili flakes (if using) and sauté for 1 minute.
Make Creamy Sauce:
Reduce heat to medium. Pour in cream and milk stirring to scrape up any browned bits. Simmer for 2–3 minutes.
Add Cheese:
Add ¾ of the mozzarella cheddar and Parmesan to the sauce. Stir until melted and smooth.
Combine:
Return the chicken to the skillet then add the cooked pasta. Toss everything together to coat well. Adjust seasoning with extra Cajun spice salt or pepper if needed.
Transfer & Top:
Transfer mixture to a lightly greased baking dish. Sprinkle remaining cheeses over the top.
Bake:
Bake for 18–20 minutes until cheese is golden and bubbly.
Garnish & Serve:
Garnish with chopped parsley and a pinch of Cajun seasoning before serving.
Tender chicken and penne pasta baked together in a rich Cajun-spiced sauce to create this pasta bake. Pin
Tender chicken and penne pasta baked together in a rich Cajun-spiced sauce to create this pasta bake. | crumbkiss.com

My family loves when I serve this dish bubbling hot from the oven it brings everyone to the table for seconds and lots of smiles. It's become a beloved weeknight meal especially when we want something exciting yet homey.

Serving Suggestions

Pair this pasta bake with a crisp green salad or warmed garlic bread for a complete meal. It also goes nicely with iced tea or a glass of Sauvignon Blanc.

Make Ahead & Storage

Assemble the pasta bake up to a day ahead and refrigerate covered then bake when ready to serve. Leftovers keep well in an airtight container in the fridge for up to 3 days.

Variations

Try adding spinach or sliced mushrooms for extra veggies. For a lighter version use half-and-half instead of heavy cream or swap in whole-wheat pasta for more fiber.

A close-up of a flavorful Cajun Chicken Pasta Bake, showing melted cheese and a hint of parsley garnish. Pin
A close-up of a flavorful Cajun Chicken Pasta Bake, showing melted cheese and a hint of parsley garnish. | crumbkiss.com

This Cajun Chicken Pasta Bake is sure to warm you up and satisfy your cravings for something creamy cheesy and packed with flavor. Enjoy every comforting bite!

Recipe FAQ

What type of pasta works best?

Penne or rigatoni are ideal as their ridged surfaces hold the creamy sauce well.

Can I adjust the spice level?

Yes, use less Cajun seasoning or omit chili flakes for a milder flavor, or add more for extra heat.

How can I make it lighter?

Substitute half-and-half for heavy cream to reduce richness while maintaining creaminess.

What cheese blend is recommended?

A mix of mozzarella, cheddar, and Parmesan provides creaminess, sharpness, and a golden crust when baked.

Can vegetables be added?

Yes, mushrooms or spinach can be added during sautéing for extra texture and nutrients.

Cajun Chicken Pasta Bake

Tender chicken, bold Cajun spices, creamy cheese, and pasta baked to golden perfection.

Prep duration
20 min
Cook duration
35 min
Complete duration
55 min


Complexity Medium

Heritage American (Cajun-inspired)

Output 4 Portions

Dietary guidelines None specified

Components

Meats

01 2 large chicken breasts, cut into bite-sized pieces

Vegetables

01 1 red bell pepper, diced
02 1 yellow bell pepper, diced
03 1 small red onion, diced
04 2 cloves garlic, minced

Pasta

01 10 ounces penne or rigatoni pasta

Sauces & Dairy

01 2 tablespoons olive oil
02 1 tablespoon butter
03 ¾ cup heavy cream
04 ½ cup milk
05 1 cup shredded mozzarella cheese
06 ½ cup grated Parmesan cheese
07 1 cup shredded cheddar cheese

Spices & Seasonings

01 1½ tablespoons Cajun seasoning, plus extra for garnish
02 ½ teaspoon smoked paprika
03 ½ teaspoon salt
04 ¼ teaspoon black pepper
05 ¼ teaspoon chili flakes (optional)

Garnish

01 2 tablespoons chopped fresh parsley

Method

Phase 01

Preheat Oven: Set the oven to 400°F (200°C) to prepare for baking.

Phase 02

Cook Pasta: Boil pasta in salted water, cooking 2 minutes less than package instructions. Drain and set aside to finish cooking in the oven.

Phase 03

Brown Chicken: Heat olive oil and butter in a large skillet over medium-high heat. Add chicken, 1 tablespoon Cajun seasoning, salt, and pepper. Sauté until golden and cooked through, about 6 to 8 minutes. Remove from skillet and set aside.

Phase 04

Sauté Vegetables: In the same skillet, cook onions and bell peppers until softened, about 4 to 5 minutes. Add garlic, smoked paprika, and chili flakes if using, sautéing for an additional minute.

Phase 05

Prepare Sauce: Reduce heat to medium, then stir in heavy cream and milk, scraping up any browned bits from the pan. Simmer for 2 to 3 minutes.

Phase 06

Add Cheeses: Incorporate three-quarters of the mozzarella, cheddar, and Parmesan cheeses into the sauce. Stir until the mixture is smooth and melted.

Phase 07

Combine Chicken and Pasta: Return the chicken to the skillet, add the cooked pasta, and toss thoroughly to coat everything evenly. Adjust seasoning with additional Cajun spice, salt, or pepper to taste.

Phase 08

Assemble Casserole: Transfer the mixture into a greased baking dish. Sprinkle the remaining cheeses uniformly over the top.

Phase 09

Bake: Bake uncovered for 18 to 20 minutes until the cheese melts and turns golden and bubbly.

Phase 10

Garnish and Serve: Sprinkle chopped fresh parsley and a pinch of Cajun seasoning before serving.

Necessary tools

  • Large skillet or sauté pan
  • Medium saucepan
  • Baking dish (approximately 2 quarts)
  • Wooden spoon
  • Chef’s knife and cutting board

Allergy details

Review each component for potential allergens and consult healthcare providers if you're uncertain.
  • Contains milk (cheese, cream, butter) and wheat (pasta). May contain gluten; verify pasta choice and spice blend for cross-contamination.

Nutritional breakdown (per portion)

These values are approximate guides only and shouldn't replace professional medical guidance.
  • Energy: 670
  • Fat: 32 g
  • Carbohydrates: 56 g
  • Protein: 40 g