Zesty Cajun Garlic Parmesan Chicken

Featured in: Cozy Weeknight Dinners

Tender chicken and cheese tortellini come together in a rich Cajun garlic Parmesan sauce, bursting with bold flavors. Quick to prepare, this fusion pasta features sautéed peppers and onions for added color and texture, finished with fresh parsley and extra Parmesan. Each bite highlights the creamy, spicy blend, making it perfect for easy weeknight dining and sure to satisfy with its comforting, hearty appeal. Pairs wonderfully with crusty bread and chilled Sauvignon Blanc.

Updated on Sat, 08 Nov 2025 13:52:00 GMT
Zesty Cajun Garlic Parmesan Chicken Tortellini drizzled with creamy sauce and fresh parsley.  Pin
Zesty Cajun Garlic Parmesan Chicken Tortellini drizzled with creamy sauce and fresh parsley. | crumbkiss.com

A vibrant and flavorful pasta dish featuring tender chicken, cheesy tortellini, and a creamy Cajun garlic Parmesan sauce. Perfect for a quick weeknight meal with a spicy kick.

I made this after a long day and was amazed how the blend of Cajun spices and Parmesan created such a satisfying dish. The tortellini soaks up all the flavor, and it's now a favorite for our pasta nights.

Ingredients

  • Chicken breasts: 2 large boneless, skinless, cut into bite-sized pieces
  • Cheese tortellini: 500 g (18 oz), refrigerated
  • Garlic: 3 cloves, minced
  • Red bell pepper: 1 small, diced
  • Yellow onion: 1 small, diced
  • Heavy cream: 1 cup (240 ml)
  • Parmesan cheese: 1/2 cup (50 g), freshly grated
  • Unsalted butter: 2 tablespoons
  • Cajun seasoning: 1 tablespoon
  • Smoked paprika: 1/2 teaspoon
  • Black pepper: 1/2 teaspoon
  • Salt: 1/2 teaspoon, plus more to taste
  • Olive oil: 2 tablespoons
  • Fresh parsley: 2 tablespoons, chopped, for garnish
  • Optional: extra grated Parmesan for serving

Instructions

Cook tortellini:
Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.
Sauté chicken:
Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5 to 7 minutes. Remove chicken from skillet and set aside.
Cook vegetables and garlic:
In the same skillet, add remaining olive oil and butter. Sauté onion and bell pepper for 3 to 4 minutes until softened. Add garlic and cook for 30 seconds until fragrant.
Make sauce:
Sprinkle in remaining Cajun seasoning and smoked paprika. Stir, then pour in the heavy cream. Bring to a gentle simmer, stirring frequently.
Add Parmesan and combine:
Add Parmesan cheese and stir until melted and sauce is smooth. Taste and adjust seasoning if needed.
Return chicken and tortellini:
Return chicken to the skillet, along with cooked tortellini. Toss gently to coat everything in the sauce.
Final cook and serve:
Cook for an additional 2 to 3 minutes until heated through. Serve garnished with fresh parsley and extra Parmesan if desired.
A deliciously vibrant bowl of Zesty Cajun Garlic Parmesan Chicken Tortellini ready to serve.  Pin
A deliciously vibrant bowl of Zesty Cajun Garlic Parmesan Chicken Tortellini ready to serve. | crumbkiss.com

My kids love sprinkling extra Parmesan on top as we gather for dinner, and there are always requests for second helpings. It's a crowd-pleaser every time.

Required Tools

You'll need a large pot for boiling tortellini, a large skillet for sautéing everything, a chefs knife, cutting board, and wooden spoon or spatula.

Allergen Information

This recipe contains wheat from the tortellini, milk from the cream and cheese, and eggs if included in the tortellini. Always check labels if sensitive.

Nutritional Information

Each serving provides about 620 calories, 29 g fat, 53 g carbohydrates, and 38 g protein.

Indulge in Zesty Cajun Garlic Parmesan Chicken Tortellini topped with extra Parmesan and herbs. Pin
Indulge in Zesty Cajun Garlic Parmesan Chicken Tortellini topped with extra Parmesan and herbs. | crumbkiss.com

Serve this comfort food hot from the skillet with a crisp white wine. Enjoy every creamy, zesty bite!

Recipe FAQ

Can I use shrimp instead of chicken?

Yes, shrimp is a delicious substitute for chicken, adding a seafood twist and complementing Cajun flavors beautifully.

Is there a way to make it spicier?

Absolutely. For more heat, add cayenne pepper or red pepper flakes to the sauce during cooking, adjusting to taste.

What type of tortellini works best?

Fresh, refrigerated cheese tortellini is ideal for this dish, providing a creamy filling that pairs well with the sauce.

Can I make it ahead of time?

It’s best enjoyed fresh, but you can prep the sauce and chicken ahead; combine with tortellini and warm gently before serving.

Which wine pairs well with this meal?

A crisp white wine, such as Sauvignon Blanc, balances the creamy and spicy notes of the sauce and complements the chicken.

Are there any allergy concerns?

Yes, this dish contains wheat, milk, and eggs. Always check tortellini packaging for specific allergens before serving.

Zesty Cajun Garlic Parmesan Chicken

Savory chicken and cheesy tortellini tossed in Cajun garlic Parmesan cream sauce. Weeknight comforting fusion.

Prep duration
15 min
Cook duration
25 min
Complete duration
40 min


Complexity Easy

Heritage American-Italian Fusion

Output 4 Portions

Dietary guidelines None specified

Components

Proteins

01 2 large boneless, skinless chicken breasts, cut into bite-sized pieces

Pasta

01 18 oz refrigerated cheese tortellini

Vegetables & Aromatics

01 3 cloves garlic, minced
02 1 small red bell pepper, diced
03 1 small yellow onion, diced

Dairy

01 1 cup heavy cream
02 1/2 cup freshly grated Parmesan cheese
03 2 tablespoons unsalted butter

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 1/2 teaspoon smoked paprika
03 1/2 teaspoon black pepper
04 1/2 teaspoon salt, plus more to taste

Oils & Garnish

01 2 tablespoons olive oil
02 2 tablespoons chopped fresh parsley, for garnish
03 Extra grated Parmesan cheese, optional for serving

Method

Phase 01

Cook Tortellini: Bring a large pot of salted water to a boil. Prepare tortellini according to package directions. Drain and set aside.

Phase 02

Brown Chicken: Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and pepper. Sauté until browned and thoroughly cooked, approximately 5 to 7 minutes. Remove chicken and set aside.

Phase 03

Sauté Vegetables: Add the remaining olive oil and butter to the same skillet. Sauté diced onion and red bell pepper for 3 to 4 minutes until softened. Incorporate garlic and cook for 30 seconds until aromatic.

Phase 04

Prepare Cream Sauce: Stir in the rest of the Cajun seasoning and smoked paprika. Pour in heavy cream, bring to a gentle simmer, stirring frequently.

Phase 05

Finish Sauce: Add Parmesan cheese, stirring until melted and sauce is smooth. Adjust seasoning to taste if needed.

Phase 06

Combine Chicken and Tortellini: Return the cooked chicken and drained tortellini to the skillet. Toss gently until coated with the sauce.

Phase 07

Heat Through: Continue cooking for 2 to 3 minutes, allowing flavors to meld and ensuring all components are warmed through.

Phase 08

Garnish and Serve: Plate and garnish with chopped fresh parsley and additional Parmesan cheese as desired.

Necessary tools

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Wooden spoon or spatula
  • Measuring cups and spoons

Allergy details

Review each component for potential allergens and consult healthcare providers if you're uncertain.
  • Contains wheat (in tortellini), milk (cream, Parmesan, butter), eggs (tortellini may contain eggs). Verify tortellini packaging for additional allergens.

Nutritional breakdown (per portion)

These values are approximate guides only and shouldn't replace professional medical guidance.
  • Energy: 620
  • Fat: 29 g
  • Carbohydrates: 53 g
  • Protein: 38 g