One-Pot Cajun Chicken Alfredo

Featured in: One-Pot Comforts

This dish brings together tender chicken tossed in smoky Cajun spices and simmered with orzo pasta in a creamy Alfredo blend. Sautéed onions, garlic, and bell peppers deepen the flavor, while Parmesan cheese adds richness. Cooked all in one pot, it offers a quick and satisfying dinner with layers of spice and creaminess complemented by fresh parsley garnish. Optional spinach adds a touch of green, making it a warm, hearty meal perfect for weeknights.

Updated on Sun, 23 Nov 2025 12:53:00 GMT
A steaming bowl of One-Pot Cajun Chicken Alfredo Orzo, a creamy and flavorful delight. Pin
A steaming bowl of One-Pot Cajun Chicken Alfredo Orzo, a creamy and flavorful delight. | crumbkiss.com

A creamy, spicy, and comforting one-pot meal combining tender chicken, smoky Cajun spices, velvety Alfredo sauce, and orzo pasta for a quick weeknight dinner.

This recipe brings together bold Cajun flavors with creamy Alfredo sauce in a single dish, making cooking and cleanup a breeze.

Ingredients

  • Chicken: 2 large boneless, skinless chicken breasts (about 450 g) cut into bite sized pieces
  • Onion: 1 small yellow onion, finely chopped
  • Garlic: 3 cloves minced
  • Red Bell Pepper: 1 diced
  • Baby Spinach: 1 cup roughly chopped (optional)
  • Olive Oil: 2 tablespoons
  • Orzo Pasta: 1 1/2 cups (300 g)
  • Chicken Broth: 2 1/2 cups (600 ml) low sodium
  • Heavy Cream: 1 cup (240 ml)
  • Milk: 1/2 cup (120 ml)
  • Cajun Seasoning: 1 tablespoon (store bought or homemade)
  • Smoked Paprika: 1/2 teaspoon
  • Salt: 1/2 teaspoon or to taste
  • Black Pepper: 1/4 teaspoon freshly ground
  • Cayenne Pepper: Pinch (optional for extra heat)
  • Parmesan Cheese: 3/4 cup (75 g) freshly grated
  • Parsley: Chopped fresh garnish
  • Extra Parmesan Cheese: For garnish

Instructions

Step 1:
Season the chicken pieces with half of the Cajun seasoning, salt, and pepper.
Step 2:
In a large, deep skillet or Dutch oven, heat olive oil over medium high heat. Add the chicken and sauté until browned and just cooked through, about 5 6 minutes. Remove chicken to a plate and set aside.
Step 3:
In the same pot, add onion and bell pepper. Sauté for 3 minutes until softened. Add garlic and cook for 1 minute more.
Step 4:
Stir in the orzo, smoked paprika, remaining Cajun seasoning, and cayenne pepper. Toast the orzo for 1 minute, stirring frequently.
Step 5:
Pour in the chicken broth, heavy cream, and milk. Stir well, scraping any browned bits from the bottom.
Step 6:
Bring to a gentle boil, then reduce heat to medium low. Cover and simmer for 10 12 minutes, stirring occasionally, until orzo is tender and most liquid is absorbed.
Step 7:
Return the chicken to the pot along with spinach (if using). Stir in Parmesan cheese until melted and creamy.
Step 8:
Taste and adjust seasoning. If sauce is too thick, add a splash more milk or broth.
Step 9:
Serve hot, garnished with parsley and extra Parmesan.
Picture creamy One-Pot Cajun Chicken Alfredo Orzo; tender chicken and orzo mingling with spices. Pin
Picture creamy One-Pot Cajun Chicken Alfredo Orzo; tender chicken and orzo mingling with spices. | crumbkiss.com

This dish has become a family favorite for busy weeknights, bringing comfort and bold flavors to our dinner table.

Tips for Best Results

Use freshly grated Parmesan for a richer taste and toast the orzo until fragrant to enhance its nutty flavor.

Variations

Swap chicken with shrimp or smoked sausage and add mushrooms or peas for extra vegetables.

Serving Suggestions

Serve with crusty bread or a green salad to complete the meal.

This photo features a vibrant plate of One-Pot Cajun Chicken Alfredo Orzo garnished with fresh parsley. Pin
This photo features a vibrant plate of One-Pot Cajun Chicken Alfredo Orzo garnished with fresh parsley. | crumbkiss.com

This Cajun chicken Alfredo orzo is sure to please with minimal effort and maximum flavor.

Recipe FAQ

Can I substitute chicken with other proteins?

Yes, shrimp or smoked sausage can be used instead of chicken for a different flavor profile.

How can I make the dish lighter?

Use half-and-half in place of heavy cream to reduce richness while maintaining creaminess.

Is it necessary to use Cajun seasoning store-bought?

Homemade Cajun seasoning works well and allows you to adjust the spice levels to taste.

Can I add more vegetables to the meal?

Yes, mushrooms, peas, or additional greens like spinach can be added for extra texture and nutrition.

What is the best way to ensure the orzo cooks evenly?

Simmer the orzo covered on medium-low heat, stirring occasionally to prevent sticking and ensure tender pasta.

How do I prevent the sauce from becoming too thick?

Add a splash of milk or broth to loosen the sauce if it thickens too much during cooking.

One-Pot Cajun Chicken Alfredo

Tender chicken and orzo meld with creamy Alfredo and smoky Cajun spices in a one-pot meal.

Prep duration
15 min
Cook duration
25 min
Complete duration
40 min


Complexity Easy

Heritage American, Cajun-inspired

Output 4 Portions

Dietary guidelines None specified

Components

Proteins

01 2 large boneless, skinless chicken breasts, cut into bite-sized pieces

Vegetables

01 1 small yellow onion, finely chopped
02 3 cloves garlic, minced
03 1 red bell pepper, diced
04 1 cup baby spinach, roughly chopped (optional)

Pantry

01 2 tablespoons olive oil
02 1 1/2 cups orzo pasta
03 2 1/2 cups low-sodium chicken broth
04 1 cup heavy cream
05 1/2 cup milk

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 1/2 teaspoon smoked paprika
03 1/2 teaspoon salt, or to taste
04 1/4 teaspoon freshly ground black pepper
05 Pinch of cayenne pepper (optional)

Cheeses

01 3/4 cup freshly grated Parmesan cheese

Garnish

01 Chopped fresh parsley
02 Extra Parmesan cheese

Method

Phase 01

Prepare chicken seasoning: Season chicken pieces with half the Cajun seasoning, salt, and black pepper.

Phase 02

Brown chicken: Heat olive oil in a large deep skillet or Dutch oven over medium-high heat. Add chicken and sauté until browned and cooked through, about 5–6 minutes. Remove and set aside.

Phase 03

Sauté vegetables: In the same pot, add onion and red bell pepper. Cook for 3 minutes until softened, then add garlic and cook for 1 more minute.

Phase 04

Toast orzo and spices: Stir in orzo, smoked paprika, remaining Cajun seasoning, and cayenne pepper. Toast for 1 minute, stirring frequently.

Phase 05

Add liquids: Pour in chicken broth, heavy cream, and milk. Stir well, scraping browned bits from the bottom.

Phase 06

Simmer orzo: Bring to a gentle boil, reduce heat to medium-low, cover, and simmer for 10–12 minutes, stirring occasionally, until orzo is tender and most liquid is absorbed.

Phase 07

Combine chicken and spinach: Return chicken to the pot along with spinach if using. Stir in Parmesan cheese until melted and creamy.

Phase 08

Adjust seasoning and serve: Taste and adjust seasoning as needed. If sauce is too thick, add a splash of milk or broth. Serve garnished with parsley and extra Parmesan.

Necessary tools

  • Large deep skillet or Dutch oven with lid
  • Cutting board and knife
  • Wooden spoon or spatula
  • Measuring cups and spoons
  • Grater for Parmesan cheese

Allergy details

Review each component for potential allergens and consult healthcare providers if you're uncertain.
  • Contains dairy (cream, milk, Parmesan) and wheat (orzo)
  • Potential celery allergen in chicken broth

Nutritional breakdown (per portion)

These values are approximate guides only and shouldn't replace professional medical guidance.
  • Energy: 570
  • Fat: 27 g
  • Carbohydrates: 48 g
  • Protein: 37 g